TY - JOUR AU1 - Castaldo, Paolo AU2 - Stratta, Robert J. AU3 - Wood, R. Patrick AU4 - Markin, Rodney S. AU5 - Patil, Kashinath D. AU6 - Shaefer, Mark S. AU7 - Langnas, Alan N. AU8 - Reed, Elizabeth C. AU9 - Li, Shujun AU1 - Pillen, Todd J. AU1 - Shaw, Byers W. AB - Abstract • During a 50-month period, we identified 91 episodes of fungal infection in 72 liver transplant recipients (23.8%). Candida species accounted for 83.5% of cases. Clinical patterns of fungal infections included disseminated infection (19), peritonitis (17), pneumonitis (15), multiple sites of colonization (13), fungemia (11), and other sites (16). The diagnosis of fungal infection was usually made in the first 2 months (84.7% of cases), at a mean time of 16 days after transplantation. Risk factors for fungal infections included retransplantation, Risk score, intraoperative transfusion requirement, urgent status, Roux limb biliary reconstruction (in adults), steroid dose, bacterial infections and antibiotic therapy, and vascular complications. Fungal infections were successfully treated with amphotericin B in 63 cases (74.1%) but were associated with diminished patient survival (50% vs 83.5%). Fungal infection is a frequent source of early morbidity and can be related to well-defined risk factors, suggesting the need for effective prophylaxis. (Arch Surg. 1991;126:149-156) References 1. Schroter GPJ, Hoelscher M, Putnam CW, et al. Fungus infections after liver transplantation . Ann Surg . 1977;186:115-122.Crossref 2. Wajszczuk CP, Dummer JS, Ho M, et al. Fungal infections in liver transplant recipients . Transplantation . 1985;40:347-353.Crossref 3. Kusne S, Dummer JS, Singh N, et al. Infections after liver transplantation: an analysis of 101 consecutive cases . 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TI - Clinical Spectrum of Fungal Infections After Orthotopic Liver Transplantation JF - Archives of Surgery DO - 10.1001/archsurg.1991.01410260033005 DA - 1991-02-01 UR - https://www.deepdyve.com/lp/american-medical-association/clinical-spectrum-of-fungal-infections-after-orthotopic-liver-D786re69TL SP - 149 EP - 156 VL - 126 IS - 2 DP - DeepDyve ER -