TY - JOUR
AU1 - Brotman, Betsy
AU2 - Prince, Alfred M.
AU3 - Huima, Tellervo
AU4 - Richardson, Linda
AU5 - Van Den Ende, M. C.
AU6 - Pfeifer, U.
AB - Pre‐existing chronic or concurrent acute non‐A, non‐B (NANB) virus infection has been found to interfere with hepatitis B virus (HBV) replication and to delay and moderate markedly the appearance of disease related to HBV infection in chimpanzees. The mechanism for this phenomenon remains unclear. These findings are of practical significance for vaccine safety testing and evaluation of methods for virus inactivation in chimpanzees. The possible occurrence of dual NANB and HBV infection requires that prolonged follow‐up be carried out. Attempts to carry out inactivation studies on materials containing both types of virus may also provide misleading observations.
TI - Interference between non‐a, non‐b and hepatitis b virus infection in chimpanzees
JF - Journal of Medical Virology
DO - 10.1002/jmv.1890110303
DA - 1983-01-01
UR - https://www.deepdyve.com/lp/wiley/interference-between-non-a-non-b-and-hepatitis-b-virus-infection-in-8PRP9xq8HR
SP - 191
EP - 205
VL - 11
IS - 3
DP - DeepDyve
ER -