TY - JOUR AU1 - Agopian, Vatche G. AU2 - Hiatt, Jonathan R. AB - Optimal Time for Re-resection for Incidental Gallbladder Cancer Original Investigation Research analysis of surgical findings and survival. J Surg Oncol. 15. Isambert M, Leux C, Métairie S, Paineau J. why and which reoperation? J Visc Surg. 2011;148 2010;102(6):620-625. Incidentally-discovered gallbladder cancer: when, (2):e77-e84. Invited Commentary Sooner or Later? Vatche G. Agopian, MD; Jonathan R. Hiatt, MD Incidental gallbladder cancer is reported in approximately They suggest that early reoperation (less than 4 weeks) may not 0.7% of patients undergoing a cholecystectomy. While the allow for an adequate assessment of advanced subclinical dis- need for surgical re-resection and staging portal lymphad- ease, while late reoperation (more than 8 weeks) may allow for enectomy in the absence of metastatic disease is not debated, dissemination of subclinical disease that remains undetected, the optimal timing of reoperation is unknown. explaining the inferior outcomes in these 2 groups. While it is Ethun and colleagues investigate this question using ret- undeniable that time allows for manifestation of subclinical dis- rospective data from the multi-institution US Extrahepatic Bili- ease, it is difficult to reconcile the authors’ contention that a few ary Malignancy Consortium database. They suggest that re- extra weeks of early observation allowed the identification of TI - The Timing of Reoperation for Incidental Gallbladder Cancer JF - JAMA Surgery DO - 10.1001/jamasurg.2016.3643 DA - 2017-02-26 UR - https://www.deepdyve.com/lp/american-medical-association/the-timing-of-reoperation-for-incidental-gallbladder-cancer-7yfxtl78HP SP - 149 EP - 149 VL - 152 IS - 2 DP - DeepDyve ER -