TY - JOUR AU1 - Yuan, William AU2 - Cook, Charles H. AU3 - Brat, Gabriel A. AB - Letters Corresponding Author: Da-Zhi Xu, MD, PhD, Department of Gastric Surgery, founders. In reality, the propensity to use REBOA is based on Sun Yat-sen University Cancer Center, 651 Dongfeng Rd E, Guangzhou 510060, baseline variables and time-dependent patient status China (xudzh@sysucc.org.cn). changes from ED arrival to REBOA insertion or from ED Published Online: August 14, 2019. doi:10.1001/jamasurg.2019.2667 arrival to the completion of hemostatic procedures. Match- Conflict of Interest Disclosures: None reported. ing analyses without considering these time-dependent vari- 1. Guo J, Xu A, Sun X, et al; The SEIPLUS Randomized Clinical Trial. Combined ables created bias in determining mortality rates; the physi- surgery and extensive intraoperative peritoneal lavage vs surgery alone for ological derangement in REBOA cases might increase the treatment of locally advanced gastric cancer: the SEIPLUS randomized clinical trial [published online March 27, 2019]. JAMA Surg. doi:10.1001/jamasurg.2019. apparent mortality rate, whereas the resuscitation time bias might decrease the apparent mortality in the REBOA group. 2. Misawa K, Mochizuki Y, Ohashi N, et al. A randomized phase III trial exploring Ideally, a time-dependent propensity score–matching analy- the prognostic value of extensive intraoperative peritoneal lavage in addition to sis should be performed, with the use of sensitivity analysis standard TI - Addressing Limitations in Case-Control Study of Patients Undergoing Resuscitative Endovascular Balloon Occlusion of the Aorta JF - JAMA Surgery DO - 10.1001/jamasurg.2019.2744 DA - 2019-12-21 UR - https://www.deepdyve.com/lp/american-medical-association/addressing-limitations-in-case-control-study-of-patients-undergoing-6dZRvgxCOd SP - 1167 EP - 1167 VL - 154 IS - 12 DP - DeepDyve ER -