TY - JOUR AU - Tampé, Robert AB - Open sesame: The proteasome complex is a nanodegradation machine that is essential for cellular protein turnover. A multivalent chelator head (MCH) was exploited for the specific binding to histidine‐tagged proteasomes, even in crude cell lysates. Acting as synthetic gatekeepers, this MCH controls the access and thus the proteolytic activity of the nanomachinery. TI - Controlling the Activity of the 20S Proteasome Complex by Synthetic Gatekeepers JF - Angewandte Chemie International Edition DO - 10.1002/anie.200600644 DA - 2006-08-25 UR - https://www.deepdyve.com/lp/wiley/controlling-the-activity-of-the-20s-proteasome-complex-by-synthetic-zwexGhBcr0 SP - 5702 EP - 5705 VL - 45 IS - 34 DP - DeepDyve ER -