TY - JOUR AU1 - Bothamley, Graham H. AU2 - Schreuder, Geziena M. T. AB - JIO 1992; 165 (March) 598 Correspondence Table I. Association between HLA (human leukocyte antigen) class II Human Leukocyte Antigen, Tuberculosis, and alleles and tuberculosis. Mycobacterium tuberculosis-Specific Antibody % positive Colleagues-We reported the association of human leukocyte for serotype antigen (HLA)-DR2 and DQw I with smear-positive pulmo­ nary tuberculosis [l] but at that time could not determine Patients Controls whether the DR or the DQ locus held the more significant associ­ 2 AlIele* (n= 101) (n = 64) RR AR/PF 95%CI ation. Since then, two histocompatability workshops have estab­ 9.lt lished the role of the 2B3 and TAl 0 specificities and have per­ ORwl5 53 29 2.77 0.34 0.16.0.43 ND DRwl6 3 3 0.01 0.89 NO mitted the distinction ofDRwl5 and DRwl6 in DR2 [2,3]. In ND DQw2 17 25 1.7 0.61 NO our study population, DRw 15 was equally associated with NO DQw5 42 33 1.2 1.44 NO DQw5 (n = 26) and DQw6 (n = 23), while DRw 16 was asso­ ND DQw6 39 17 3.9 2.07 NO ciated with DQw5 (n = 3); these relationships have been con­ -0.19. -0.76 DQw7 62 83 7.7 0.35 -0.54 firmed by DNA typing in other Indonesian populations [4] (un­ ND TI - Human Leukocyte Antigen, Tuberculosis, and Mycobacterium tuberculosis-Specific Antibody JF - The Journal of Infectious Diseases DO - 10.1093/infdis/165.3.598 DA - 1992-03-01 UR - https://www.deepdyve.com/lp/oxford-university-press/human-leukocyte-antigen-tuberculosis-and-mycobacterium-tuberculosis-zV0J09l0C0 SP - 598 EP - 598 VL - 165 IS - 3 DP - DeepDyve ER -