TY - JOUR AU - Zhang, Paul J. AB - ORIGINAL ARTICLE The Presence of Micropapillary Features and Retraction Artifact in Core Needle Biopsy Material Predicts Lymph Node Metastasis in Breast Carcinoma Geza Acs, MD, PhD,*w z Gyorgy Paragh, MD,w Shang-Tian Chuang, DO,* Christine Laronga, MD,z and Paul J. Zhang, MDy (Am J Surg Pathol 2009;33:202–210) Abstract: Retraction artifact around tumor cell nests is a characteristic feature of invasive micropapillary carcinoma (IMPC), a special type of breast cancer commonly associated with nodal metastasis. We have recently reported that the extent n most solid tumors, including breast cancer, the spread of retraction artifact in usual invasive ductal carcinomas (IDC) Iof cancer cells via the lymphatics to regional lymph is also a strong predictor of nodal metastasis. We examined nodes (LNs) is an important early event during tumor 32,34 whether the presence and extent of micropapillary features and progression, and nodal metastasis is a key factor in retraction artifact in core needle biopsy of breast cancers can the staging of breast cancers. Despite the major role predict nodal metastasis in a prospective series of 47 IMPC and for the lymphatics in the initial spread of cancers, little 424 IDC. Micropapillary features were present on core needle is known about the mechanisms TI - The Presence of Micropapillary Features and Retraction Artifact in Core Needle Biopsy Material Predicts Lymph Node Metastasis in Breast Carcinoma JO - American Journal of Surgical Pathology DO - 10.1097/PAS.0b013e318185e171 DA - 2009-02-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/the-presence-of-micropapillary-features-and-retraction-artifact-in-z0EQLElWqW SP - 202 EP - 210 VL - 33 IS - 2 DP - DeepDyve ER -