TY - JOUR AB - S76 Workshop 2: Immunologic Aspects of Pandemic Influenza The workshop focussed on the role of humoral and cellular directed to type-common epitopes of the virus could play a immune responses in pandemic influenza. The specific topics significant role in modulating the severity of infection and the panel were asked to address were as follows: subsequent morbidity. There is also a limited amount of data • What is needed for targeted research efforts in experimental supporting the hypothesis that sIgA, perhaps because of its and human research to better define the role of the immune dimeric nature, may be more likely to exhibit cross-reactivity system in protection and recovery? with new glycoprotein subtypes. • What immune factors regulate susceptibility and are involved The panel was divided regarding which types of live attenuated in recovery? Does cellular immunity play a role in resis- vaccine should be used. Some favored the view that an attenuated tance? If not, why not? vaccine with surface glycoproteins of a subtype currently not in The group agreed that host defense mechanisms against in- circulation (e.g., H2N2) would not encounter neutralizing anti- fluenza are fairly well understood for experimental animals, body in the respiratory tract. Such a TI - Workshop 2: Immunologic Aspects of Pandemic Influenza JF - Journal of Infectious Diseases DO - 10.1086/514182 DA - 1997-08-01 UR - https://www.deepdyve.com/lp/oxford-university-press/workshop-2-immunologic-aspects-of-pandemic-influenza-yQv0xntuOB SP - S76 EP - S77 VL - 176 IS - Supplement_1 DP - DeepDyve ER -