TY - JOUR AU1 - Kooij,, R.J.van AU2 - Velde,, E.R.te AB - Abstract Human zonae pellucidae were added to suspensions of capacitating spermatozoa. The zonae were prepared from oocytes that remained unfertilized in our in-vitro fertilization (IVF) programme. After capacitation, zona free hamster oocytes were added and the penetration rate of the hamster oocytes was determined. Controls without the addition of zonae were run in parallel. A distinct enhancement of the penetration rate was found when zonne were present during capacitation, using sperm of fertile donors. Sperm of several infertile men did not respond to the presence of zonae with higher penetration rates It was conduded that the zona peilucida is Involved in the induction of the acrosome-reaction of human spermatozoa. In addition the incubation system with zonae as described might be useful for the identification of infertile semen. zona pellucida, fertilization, acrosome reaction, hamster oocyte test, infertility This content is only available as a PDF. © 1988 IRL Press Ltd. TI - The presence of zonae pellucidae influences fusion rates between spermatozoa and zona free hamster oocytes JF - Human Reproduction DO - 10.1093/oxfordjournals.humrep.a136782 DA - 1988-08-01 UR - https://www.deepdyve.com/lp/oxford-university-press/the-presence-of-zonae-pellucidae-influences-fusion-rates-between-xuoCARGkpi SP - 773 EP - 775 VL - 3 IS - 6 DP - DeepDyve ER -