TY - JOUR
AU - Hektoen, Ludvig
AB - LUDVIG HE KTOE N. (From the Memorial Institute for Infectious Diseases, Chicago.) WHETHER the opsonic function of serum and other fluids is dependent on distinct and independent units or on antibodies with other actions as well is an interesting question concerning which there is difference of opinion. Savtchenko' believed that a quantity of fixator in itself insufficient to produce solution of red corpuscles might nevertheless be sufficient to cause their phagocytosis after becoming fixed to them, and, as is well known, Metchnikoff and his followers have held that immune serum may owe its specific powers to substances that stimulate leucocytes directly to phagocytosis at the same time as bacteria or corpuscles that take up fixator are thereby made phagocytable. In 19°5 Dean on finding a thermostable opsonic substance in immune serum assumed on the basis of Ehrlich's theory that a small amount of such substance is present in normal serum; the diminution in opsonic power observed on heating serum, immune as well as normal, was regarded as indicating combined action by two elements, one labile and one stable. Keith- urged several considerations against this view and held that if amboceptor-like action is accepted, the existence of special thermostable opsoniferous 
TI - Opsonins Distinct From Other Antibodies
JF - Journal of Infectious Diseases
DO - 10.1093/infdis/6.1.78
DA - 1909-02-18
UR - https://www.deepdyve.com/lp/oxford-university-press/opsonins-distinct-from-other-antibodies-xrWbmlurvi
SP - 78
EP - 89
VL - 6
IS - 1
DP - DeepDyve
ER -