TY - JOUR
AB - References 1 GALA Trial Collaborative Group . General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre randomised controlled trial . Lancet 2008 ; 372 : 2132 – 2142 . Crossref Search ADS PubMed WorldCat The study included 3526 carotid endarterectomies. The 30-day death, stroke or myocardial infarction rate was 84 (4·8 per cent) patients after general anaesthetic surgery compared to 80 (4·5 per cent) after a local anaesthetic procedure. 2 Mas J-L , Trinquart L, Leys D, Albucher JF, Rousseau H, Viguier A et al. Endarterectomy versus angioplasty in patients with symptomatic severe carotid stenosis (EVA–3S) trial: results up to 4 years from a randomised, multicentre trial . Lancet Neurology 2008 ; 7 : 885 – 892 . Google Scholar Crossref Search ADS PubMed WorldCat After four years, the risk of ipsilateral stroke or death was higher in the angioplasty and stenting group (11·1 versus 6·2 per cent, P = 0·03), but the difference was largely due to the higher procedural risk of stenting. Late strokes were rare after both procedures in this study that included 527 patients. 3 Eckstein H-H , Ringleb P, Allenberg J-R, Berger J, Fraedrich G, Hacke W et al. Results of the stent-protected angioplasty versus carotid endarterectomy (SPACE) study to treat symptomatic stenoses at 2 years: a multinational, prospective, randomised trial . Lancet Neurology 2008 ; 7 : 893 – 902 . Google Scholar Crossref Search ADS PubMed WorldCat After two years the ipsilateral stroke rate was 9·5 per cent after stenting compared with 8·8 per cent after surgery (P = 0·62) in this trial that included 1214 procedures. Recurrent stenosis (>70 per cent) was higher after stenting: 10·7 versus 4·6 per cent, P = 0·0007. 4 The MIMIC Trial Participants . The adjuvant benefit of angioplasty in patients with mild to moderate intermittent claudication (MIMIC) managed by supervised exercise, smoking cessation advice and best medical therapy: results from two randomised trials for stenotic femoropopliteal and aortoiliac disease . Eur J Vasc Endovasc Surg 2008 ; 36 : 680 – 688 . Crossref Search ADS PubMed WorldCat A total of 127 patients were included. After 24 months, the addition of angioplasty improved both initial claudication distance, and the absolute walking distance by 38 per cent for femoropopliteal disease and 78 per cent in aortoiliac disease. Quality of life was not affected. 5 Gisbertz SS , Ramzan M, Tutein Nolthenius RP, van der Laan L, Overtoom TThC, Moll FL et al. Short-term results of a randomized trial comparing remote endarterectomy and supragenicular bypass surgery for long occlusions of the superficial femoral artery (The REVAS Trial) . Eur J Vasc Endovasc Surg 2009 ; 37 : 68 – 76 . Google Scholar Crossref Search ADS PubMed WorldCat After two years patency was equivalent in the two groups: 61 per cent for endarterectomy and 73 per cent for bypass. Patients that had a vein bypass had the best results: 89 per cent primary patency at one year. Hospital stay was shorter after endarterectomy: median four versus six days, P = 0·004. 6 Belch J , MacCuish A, Campbell I, Cobbe S, Taylor R, Prescott R et al. The prevention of progression of arterial disease and diabetes (POPADAD) trial: factorial randomised placebo controlled trial of aspirin and antioxidants in patients with diabetes and asymptomatic peripheral arterial disease . BMJ 2008 ; 337 : 1030 – 1034 . Google Scholar OpenURL Placeholder Text WorldCat This was a four-way study that included 1276 patients with diabetes. There was no evidence that aspirin, an antioxidant, or the combination affected the rate of cardiovascular events in this high risk population. 7 Grant AM , Wileman SM, Ramsay CR, Mowat NA, Krukowski ZH, Heading RC et al. Minimal access surgery compared with medical management for chronic gastro-oesophageal reflux disease: UK collaborative randomised trial . BMJ 2009 ; 337 : 81 – 84 . Google Scholar OpenURL Placeholder Text WorldCat This complex trial included 357 randomized and 453 preference patients with reflux for at least twelve months. Disease-specific quality of life favoured the group randomized to surgery after one year, and only 38 per cent in this group were taking antireflux medication compared to 90 per cent of the medical group. 8 Lundell L , Attwood S, Ell C, Fiocca R, Galmiche J-P, Hatlebakk J et al. Comparing laparoscopic antireflux surgery with esomeprazole in the management of patients with chronic gastro-oesophageal reflux disease: a 3-year interim analysis of the LOTUS trial . Gut 2008 ; 57 : 1207 – 1213 . Google Scholar Crossref Search ADS PubMed WorldCat The main outcome measure was time to treatment failure (symptomatic relapse) in this study of 554 patients. After three years the number remaining in remission was similar: 90 per cent after surgery and 93 per cent after medical treatment, P = 0·25. 9 Ezer A , Nursal TZ, Colakoglu T, Noyan T, Moray G, Haberal M. The impact of gallbladder aspiration during elective laparoscopic cholecystectomy: a prospective randomized study . Am J Surg 2008 ; 196 : 456 – 459 . Google Scholar Crossref Search ADS PubMed WorldCat Aspiration of the gallbladder before dissection did not affect subsequent perforation rate, spillage or wound infection in this study that included 160 procedures. 10 Purkayastha S , Tilney HS, Darzi AW, Tekkis PP. Meta-analysis of randomised studies evaluating chewing gum to enhance postoperative recovery following colectomy . Arch Surg 2008 ; 143 : 788 – 793 . Google Scholar Crossref Search ADS PubMed WorldCat The analysis included five trials consisting of 158 patients. Chewing gum speeded up the return of gut function and appeared to reduce length of hospital stay: weighted mean difference 1·25 days (95 per cent confidence interval − 3·27 to 0·77 days, P = 0·23). Article PDF first page preview Close This content is only available as a PDF. Copyright © 2009 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd. This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model (https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model) Copyright © 2009 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
TI - Scientific surgery
JF - British Journal of Surgery
DO - 10.1002/bjs.6580
DA - 2009-02-17
UR - https://www.deepdyve.com/lp/oxford-university-press/scientific-surgery-xZhaL2XVVZ
SP - 324
EP - 324
VL - 96
IS - 3
DP - DeepDyve
ER -