TY - JOUR
AU1 - Lin, Guang-Tan
AU2 - Chen, Jun-Yu
AU3 - Chen, Qi-Yue
AU4 - Que, Si-Jin
AU5 - Liu, Zhi-Yu
AU6 - Zhong, Qing
AU7 - Wang, Jia-Bin
AU8 - Lin, Jian-Xian
AU9 - Lu, Jun
AU1 - Lin, Mi
AU1 - Huang, Ze-Ning
AU1 - Xie, Jian-Wei
AU1 - Li, Ping
AU1 - Huang, Chang-Ming
AU1 - Zheng, Chao-Hui
AB - ObjectiveTotally laparoscopic total gastrectomy (TLTG) and laparoscopic-assisted total gastrectomy (LATG) are two types of minimally invasive radical gastrectomy procedures to treat gastric cancer (GC). This study compared the long-term prognosis and postoperative health-related quality of life (HRQoL) between TLTG and LATG.MethodsA total of 106 patients who underwent TLTG and 1,076 patients who underwent LATG at the Union Hospital of Fujian Medical University (Fuzhou, China) between January 2014 and April 2018 were included in the propensity score matching (PSM, 1:2). Patient-reported outcomes at 3, 6, and 12 months after gastrectomy were analyzed. The questionnaire referred to the European Organization for Research and Treatment of Cancer (EORTC) 30-item core QoL (QLQ-C30)and the GC module (QLQ-STO22) questionnaire.ResultsAfter PSM, there were no significant differences in clinicopathological characteristics between the TLTG (n = 104) and the LATG groups (n = 208). Operative time and volume of blood loss were significantly lower in the TLTG group than in the LATG group. Kaplan-Meier survival analysis revealed similar 3-year survival rates between the TLTG and LATG groups (83.7 vs. 80.3%, respectively; P = 0.462). Tolerance to nonliquid diet, decrease in body weight, and albumin levels were also significantly lower in the TLTG group than in the LATG group (all P < 0.05). The HRQoL scale demonstrated that the overall score in the TLTG group was better than that in the LATG group at 3, 6, and 12 months after gastrectomy (all P < 0.05).ConclusionsPatients with GC undergoing TLTG reported better HRQoL and experienced faster recovery of social function than those undergoing LATG, although the two groups demonstrated similar short-term outcomes and long-term prognosis.
TI - Patient-Reported Outcomes of Individuals with Gastric Cancer Undergoing Totally Laparoscopic Versus Laparoscopic-Assisted Total Gastrectomy: A Real-World, Propensity Score-Matching Analysis
JF - Annals of Surgical Oncology
DO - 10.1245/s10434-022-12764-x
DA - 2023-03-01
UR - https://www.deepdyve.com/lp/springer-journals/patient-reported-outcomes-of-individuals-with-gastric-cancer-xMp0RORIan
SP - 1759
EP - 1769
VL - 30
IS - 3
DP - DeepDyve
ER -