TY - JOUR AU - Carpenter, Charles M. AB - MIXED INFECTION IN GUINEA-PIGS WITH BACTERIUM ABORTUM AND MYCOBACTERIUM TUBERCULOSIS A D A L Y N F. S C HOE N FE L D AND C H A R L E 5 M. CAR PEN T E R From the Diagnostic Laboratory, Department qf Pathology and Bacteriology New York State Veterinary College at Cornell University, Ithoca Ever since Smith and Fabyan 1 observed that Bacterium abortum produces a disease in guinea-pigs, the lesions of which are similar to tuberculosis, these animals have been used extensively in studies on the disease due to the Bang organism. In examining the tissues of cattle for the presence of infection with Bacterium abortum, it was found necessary to inject extracts of lymph glands into guinea-pigs. Although there were no gross lesions of tuberculosis in the tissues which were injected, it was observed that some of the guinea-pigs became infected with this disease. The question arose whether guinea-pigs suffering from tuberculosis would show the presence of Bacterium abortum should the tissues with which the guinea-pigs were injected be infected with both organisms. The presence of Bacterium abort urn in guinea-pigs is determined as follows: (1) by the occurrence of typical macroscopic lesions, such as TI - Mixed Infection in Guinea-Pigs with Bacterium Abortum and Mycobacterium Tuberculosis JF - The Journal of Infectious Diseases DO - 10.1093/infdis/37.1.68 DA - 1925-07-01 UR - https://www.deepdyve.com/lp/oxford-university-press/mixed-infection-in-guinea-pigs-with-bacterium-abortum-and-wsfQVQVzUP SP - 68 EP - 74 VL - 37 IS - 1 DP - DeepDyve ER -