TY - JOUR
AU - Das, Dilip K.
AB - Fine Needle Aspiration A Diagnostic Aid in Neoplasms of T-Cell Lineage? Dilip K. Das, MBBS, M.D., Ph.D., D.Sc., FRCPath, M.I.A.C. Objective cleoli in 60% of cells and a diffuse cytoplasmic reaction for To determine whether CD20 nucleolar positivity can serve CD 20 in 5% of cells. as a diagnostic aid in T-cell neoplasms. Conclusion Study Design If our observation is corroborated by other studies, CD20 During a period of 5 years (1998–2002), 125 lymphoma nucleolar positivity may serve as a diagnostic aid in T-cell cases consisting of 78 non- neoplasms. (Acta Cytol 2005; Hodgkin’s lymphoma (NHL), 49:365–372) CD20-expressing T-cell lymphomas, 38 Hodgkin’s disease (HD) and 9 NHL/HD were diag- even if nucleolar staining is noted, nosed by fine needle aspiration Keywords: CD20 antigen, should not be misdiagnosed as B-cell (FNA) cytology. In FNA cell nucleolus, non-Hodgkin's smears of NHL, the 2 most lymphoma, the prognosis of which lymphoma. commonly used antibodies for is different. immunocytochemical staining 26 (CD20) and CD3, were CD3 (29 cases) and Lwhich detect cytoplas- CD20 (33 cases). A case was considered positive if ≥ 50% of mic domains of corresponding antigens, are the most cells showed a positive reaction. sensitive and specific antibodies for identifying 
TI - Nucleolar Positivity for CD20
JF - Acta Cytologica
DO - 10.1159/000326167
DA - 2011-01-01
UR - https://www.deepdyve.com/lp/karger/nucleolar-positivity-for-cd20-wcWasQ9kgL
SP - 365
EP - 372
VL - 49
IS - 4
DP - DeepDyve
ER -