TY - JOUR
AU - Perfect, John, R.
AB - Abstract We present four cases of disseminated zygomycosis that illustrate the characteristic clinical syndromes and natural history of this infection. The zygomycetes affect individuals immunosuppressed by age, drug therapy, or underlying disease. A previous splenectomy or deferoxamine therapy may be an additional factor in the development of disseminated zygomycosis. Clinical syndromes reflect vascular invasion and organ infarction. Diagnosis requires consideration of risk factors followed by biopsy of the affected organ for culture and for demonstration of broad nonseptate hyphae in tissue sections. Despite advancesin the management of many bacterial and fungal infections in the immunosuppressed host, the results of therapy for disseminated zygomycosis remain dismal. This content is only available as a PDF. Author notes Please address requests for reprints to Dr. Christopher W. Ingram, Box 3538, Duke University Medical Center, Durham, North Carolina 27710. © 1989 by The University of Chicago
TI - Disseminated Zygomycosis: Report of Four Cases and Review
JF - Clinical Infectious Diseases
DO - 10.1093/clinids/11.5.741
DA - 1989-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/disseminated-zygomycosis-report-of-four-cases-and-review-w8lCpVlCXM
SP - 741
EP - 754
VL - 11
IS - 5
DP - DeepDyve
ER -