TY - JOUR
AU - Von Zur Mühlen, A
AB - cultures and subcultures of from In human as well as from different primary thyrocytes goiters nodules within a we observed Cell division of human single goiter widely varying growth patterns. and even of cloned FRTL-5 cells is not distributed a but culture, thyrocytes randomly throughout cells tend to in clusters of variable size. Stimulation of IGF-1 or dividing gather thyrocytes by TSH, EGF increases rates with differences of rates between cultures derived growth great proliferation from different An increase in the number of cells is achieved recruitment from goiters. dividing by a of cells. pool poorly responding In the studies the that the tremendous of conclusion, support concept heterogeneity thyroid in vivo has its and even its source in the intercellular differences be¬ growth counterpart perhaps - - tween the in cultures of human multinodular and even in cultures single thyrocytes generated goiters of cloned FRTL-5 cells. References F.: and its variants: and 1. Studer, H., Ramelli, multinodular En- Simple goiter euthyroid hyperthyroid goiters. docr. Rev. 3 40-61 (1982), 2. H. M. E.: of and of Peter, J., Gerber, H., Studer, H., Becker, V., Peterson, iodine metabolism growth Autonomy nude mice. J. Clin. Invest. 80 491^198 in feline onto 
TI - Prospective study of the postpartum thyroid function in healthy women
JO - European Journal of Endocrinology
DO - 10.1530/acta.0.120s046
DA - 1989-06-01
UR - https://www.deepdyve.com/lp/oxford-university-press/prospective-study-of-the-postpartum-thyroid-function-in-healthy-women-w0sb0I5C8k
SP - S46
EP - S47
VL - 120
IS - 3_Supplement
DP - DeepDyve
ER -