TY - JOUR AU - Rae, Caroline D. AB - pii: sp-00674-14 http://dx.doi.org/10.5665/sleep.4230 EDITORIAL Commentary on Plante et al. Gray matter-specific changes in brain bioenergetics after acute sleep deprivation: a P magnetic resonance spectroscopy study at 4 Tesla. SLEEP 2014;37:1919-1927. Caroline D. Rae, PhD Neuroscience Research Australia and School of Medical Sciences, The University of New South Wales, Barker St, Randwick, NSW, 2031 Australia In this issue, Plante and colleagues look at the effect of a deprivation showed decreased N-acetylaspartate (a mitochon- night of sleep deprivation on brain bioenergetics measured by drial and neuronal marker) and decreased total choline in eight 31 9 P magnetic resonance spectroscopy (MRS) in eight healthy healthy women, consistent with impaired energy metabolism. young individuals. Interestingly, the study includes investiga- It is also not possible to infer from the report by Plante et tion of bioenergetic changes after the subsequent two nights of al., the extent to which heterogeneity in the response to sleep 10 31 restorative sleep, and it reveals that the impact of a night’s lost deprivation influenced the results. The early P study of sleep sleep takes some time for the brain to resolve. deprivation by Murashita et al. suggested that there might be The study confirms that a night without TI - The Energetic Cost of a Night on the Town JF - SLEEP DO - 10.5665/sleep.4230 DA - 2014-12-01 UR - https://www.deepdyve.com/lp/oxford-university-press/the-energetic-cost-of-a-night-on-the-town-vqAqCyYNAR SP - 1881 EP - 1882 VL - 37 IS - 12 DP - DeepDyve ER -