TY - JOUR
AU - Zhai, Honglin
AB - A new method for the determination of human serum albumin (HSA) was developed using gold nanoclusters (AuNCs) as a probe. DNA-templated gold nanoclusters with single-stranded DNA as a template were successfully synthesized as a target probe for HSA. The mechanism studies showed that the fluorescence of AuNCs produced a clear enhanced fluorescent signal in the presence of HSA via fluorescence resonance energy transfer. Under optimal conditions, the linear range was 0.05–10 μM with the limit of detection of 13 nM. AuNCs were successfully applied to recognize and quantify HSA in human serum samples. This study demonstrates that AuNCs are a promising tool for clinical and fast detection of HSA.
TI - DNA-Templated Gold Nanoclusters for Fluorescence Resonance Energy Transfer-Based Human Serum Albumin Detection
JF - Journal of Analytical Chemistry
DO - 10.1134/s1061934822020113
DA - 2022-02-01
UR - https://www.deepdyve.com/lp/springer-journals/dna-templated-gold-nanoclusters-for-fluorescence-resonance-energy-vpBJjnOUFI
SP - 216
EP - 223
VL - 77
IS - 2
DP - DeepDyve
ER -