TY - JOUR
AU1 - Okada, Rieko
AU2 - Yasuda, Yoshinari
AU3 - Tsushita, Kazuyo
AU4 - Wakai, Kenji
AU5 - Hamajima, Nobuyuki
AU6 - Matsuo, Seiichi
AB - Background The purpose of this study is to determine the association of dipstick-determined trace proteinuria with metabolic syndrome (MetS) and its components in each age, gender, and eGFR category among a large general population. Methods A total of 270,190 people (102,223 men and 167,967 women) aged 40–74 years were included. Subjects were categorized as having negative, trace, and positive proteinuria by the dipstick method. Results The prevalence of MetS increased with increasing levels of proteinuria in any estimated glomerular filtration rate (eGFR) category (odds ratios for MetS relative to negative proteinuria: 1.22, 1.23, and 1.25 for trace proteinuria, and 2.19, 1.81, and 1.80 for positive proteinuria among subjects with eGFR of ≥ 90, 60–89, and 45–59 ml/min/1.73 m , respectively). These associations were statistically significant in each age and sex category. Among MetS components, the prevalence of hypertension and diabetes increased with increasing levels of proteinuria (odds ratios for hypertension: 1.23 and 1.87, and odds ratios for diabetes: 1.28 and 2.18 for trace and positive proteinuria, respectively), which were similarly observed in any eGFR category. There were little or no differences in the prevalence of abdominal obesity and dyslipidemia (reduced HDL-cholesterol and/or elevated triglycerides) between the levels of proteinuria. Conclusion Subjects with 
TI - Trace proteinuria by dipstick screening is associated with metabolic syndrome, hypertension, and diabetes
JF - Clinical and Experimental Nephrology
DO - 10.1007/s10157-018-1601-3
DA - 2018-06-22
UR - https://www.deepdyve.com/lp/springer-journals/trace-proteinuria-by-dipstick-screening-is-associated-with-metabolic-vlimudBIRX
SP - 1387
EP - 1394
VL - 22
IS - 6
DP - DeepDyve
ER -