TY - JOUR AU1 - Granata, Antonino AU2 - Amata, Michele AU3 - Ligresti, Dario AU4 - Martino, Alberto AU5 - Tarantino, Ilaria AU6 - Barresi, Luca AU7 - Traina, Mario AB - Background and aims Post-GI surgical wall defects are frequent and life-threatening complications, with limited literature regarding current treatment. This case series aims to assess the safety, feasibility, and outcomes of endoluminal therapy with the overstitch endoscopic suturing system (Apollo Endosurgery Inc, Austin). Materials and methods All patients who underwent endoscopic suturing for post-surgical wall defect management at IRCCS- ISMETT Palermo from October 2017 until January 2019 were retrospectively enrolled. Stratification therapy was applied according to the clinical scenario, time from surgery to endoscopic intervention, and structural condition of the wall defect layers (tissue status and suture feasibility). The therapeutic endoscopic strategy was divided into three groups (A: pure endo- scopic direct suture; B: combined therapy with endoscopic direct suture + FC-SEMS placement + anchoring; C: FC-SEMS placement + anchoring). Success was considered the resolution of symptoms and the presence of a regular intestinal transit after a period of 4–6 weeks. Results Twenty (20) patients (male/female 7/13; mean age 54 ± 13.43 years) were included in the study (group A: 9 patients, group B: 7 patients, group C: 4 patients). The types of operative procedures were bariatric (9/20), post-tracheostomy (3/20), post-operative GI surgery (8/20). The post-surgical defects were predominantly intermediate and chronic TI - Endoscopic management of post-surgical GI wall defects with the overstitch endosuturing system: a single-center experience JF - Surgical Endoscopy DO - 10.1007/s00464-019-07145-7 DA - 2019-10-03 UR - https://www.deepdyve.com/lp/springer-journals/endoscopic-management-of-post-surgical-gi-wall-defects-with-the-vainYMQPRR SP - 1 EP - 13 VL - OnlineFirst IS - DP - DeepDyve ER -