TY - JOUR AU1 - J. A. Daubenspeck AB - Medical School, Hanover, New Hampshire DAUBENSPECK, J. ANDREW. VentiZatory responses to eZastic at constant PA ~0, hypercapnic hyperpnea. J. Appl. Physiol.: Respirat. Environ. Exercise Physiol. 47(4): 778-786, 1979.- loads of 9 cmHZO/l were suddenly applied to the external airways of four normal subjects durg hypercapnic hyperpnea of 20-32 l/m usg a closed-circuit breathg apparatus that permitted alveolar carbon dioxide pressure (PA(~~.,) to be held nearly constant spite of -duced changes ventilation. Transient depression of mute ventilation (v) and mean spiratory flow (VT/TI) was observed immediately on ; both these variables creased progressively to steady levels less than control without significant changes alveolar chemistry. Two subjects creased VT (volume compensators) whereas the other two chose to crease f (frequency compensators). The net result v and VT/TI compensation was not different between these groups. Load removal always resulted an overshootg response of V lastg for several breaths and due entirely to an overshoot VT because f transiently fell to or below control at once. always resulted a steeper plot of ~-VT the steady state; three of the subjects, the transition to this steeper le was immediate. The steady-state responses were qualitatively though not quantitatively consistent with adaptation appropriate to mimize TI - Ventilatory responses to elastic loading at constant PACO2 hypercapnic hyperpnea JF - Journal of Applied Physiology DA - 1979-10-01 UR - https://www.deepdyve.com/lp/the-american-physiological-society/ventilatory-responses-to-elastic-loading-at-constant-paco2-hypercapnic-vJSD9WezSP VL - 47 IS - DP - DeepDyve ER -