TY - JOUR
AU - Verduga, R.
AB - We present the case of a woman undergoing treatment with acenocoumarol for deep vein thrombosis, who maintained an international normalized ratio (INR) of between 2.5 and 4 for 2 months. Seven days after the introduction of amoxycillin (500 mg/8 h) for a probable respiratory infection, the patient developed spontaneous bruising, with an INR of 7.1. Treatment with amoxycillin was discontinued, and 3 weeks later the INR had returned to previous values. In this case, the increase in the INR value with associated bruising after the addition of amoxycillin suggests a drug interaction between acenocoumarol and amoxycillin, other possible causes having been eliminated.
TI - Probable Acenocoumarol-Amoxycillin Interaction
JF - Acta Haematologica
DO - 10.1159/000204457
DA - 1993-01-01
UR - https://www.deepdyve.com/lp/karger/probable-acenocoumarol-amoxycillin-interaction-uy05MX06Vt
SP - 195
EP - 197
VL - 90
IS - 4
DP - DeepDyve
ER -