TY - JOUR AU - Giannini, Sandro AB - International Orthopaedics (SICOT) (2015) 39:893–900 DOI 10.1007/s00264-015-2685-y ORIGINAL PAPER Regenerative treatment in osteochondral lesions of the talus: autologous chondrocyte implantation versus one-step bone marrow derived cells transplantation Roberto Buda & Francesca Vannini & Francesco Castagnini & Marco Cavallo & Alberto Ruffilli & Laura Ramponi & Gherardo Pagliazzi & Sandro Giannini Received: 30 December 2014 /Accepted: 11 January 2015 /Published online: 8 February 2015 SICOT aisbl 2015 Abstract Conclusions To date, ACI and BMDCT showed to be effec- Purpose Osteochondral lesions of the talus (OLT) usually re- tive regenerative techniques for the treatment of OLT. quire surgical treatment. Regenerative techniques for hyaline BMDCT could be preferred over ACI for the single step pro- cartilage restoration, like autologous chondrocytes implanta- cedure, patients’ discomfort and lower costs. tion (ACI) or bone marrow derived cells transplantation (BMDCT), should be preferred. The aim of this work is com- . . paring two clusters with OLT, treated with ACI or BMDCT. Keywords Ankle Osteochondral lesions Regenerative . . Methods Eighty patients were treated with regenerative tech- techniques Bone marrow Autologous chondrocytes niques, 40 with ACI and 40 with BMDCT. The two groups implantation T2 mapping were homogenous regarding age, lesion size and depth, pre- vious TI - Regenerative treatment in osteochondral lesions of the talus: autologous chondrocyte implantation versus one-step bone marrow derived cells transplantation JF - International Orthopaedics DO - 10.1007/s00264-015-2685-y DA - 2015-02-08 UR - https://www.deepdyve.com/lp/springer-journals/regenerative-treatment-in-osteochondral-lesions-of-the-talus-usOkImjI5J SP - 893 EP - 900 VL - 39 IS - 5 DP - DeepDyve ER -