TY - JOUR
AU - Meyer, L.M.
AB - Acta hacmat. 41: 341-348 (1969) Division of Hematology, Long Island Jewish Hospital, Queens Hospital Center Affiliation, Jamaica, N.Y. Vitamin B12 Absorption Test1 S. N. A r k u n , I. F. M i l l e r a n d L. M . M e y e r Before 1953, the only definite laboratory test for diagnosis o f p erni­ cious anem ia (PA) was in vivo testing o f p atient’s gastric juice for intrinsic factor (IF) activity, w hich was a cumbersome technique. Since the introduction o f cobalt-labelled vitamin B12 in 1952 [8] four methods o f evaluation of vitam in B12 absorption have been described : fecal excretion [8], u rinary excretion [12], hepatic uptake [7], and plasm a level determ ination o f radioactive vitamin B12 [2, 5]. For obvious reasons the u rinary excretion method o f S c h i l l i n g [ 1 2 ] (or its modifications) has been widely used. Disadvantages o f this method are a) difficulties of collecting the 24 h urine specimen, b) low results in chronic kidney disease, c) adm inistration of a large dose of ‘cold’ vitam in B12 
TI - Vitamin B12 Absorption Test
JF - Acta Haematologica
DO - 10.1159/000208871
DA - 2009-01-01
UR - https://www.deepdyve.com/lp/karger/vitamin-b12-absorption-test-uZPOs5HJfe
SP - 341
EP - 348
VL - 41
IS - 6
DP - DeepDyve
ER -