TY - JOUR
AU - Highet, A. S.
AB - Viewpoints in dermatology Correspondence Correspondence 5% Doxepin cream to treat persistent lichenification and weal response to histamine and a reduced flare to in a child substance P, have both been noted on application of doxepin cream indicating that systemic absorption can occur. As with Sir, Lichen simplex develops due to persistent scratching or oral doxepin, the principal side-effect seen with topical doxepin rubbing by the patient. It may occur initially as the result of a is sedation. Although treatment of less than 10% body surface pruritic dermatosis, although once present, will itself increase area is recommended, previous reports have described a degree the intensity of the itch. We describe a young child with of sedation in over 50% of patients treating an area smaller persistent and hitherto refractory lichen simplex, who than this. There is also a report of severe respiratory depres- responded well to 5% doxepin cream. sion occurring, in a child in whom topical doxepin had been A 12-month-old boy presented with a history of intense used. However, in that case the child had active eczema and pruritus of the lower leg. The skin changes were localized to a doxepin was applied to most of the body, 
TI - 5% Doxepin cream to treat persistent lichenification in a child
JF - Clinical and Experimental Dermatology
DO - 10.1046/j.1365-2230.2001.00770.x
DA - 2001-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/5-doxepin-cream-to-treat-persistent-lichenification-in-a-child-u408k4Hkhn
SP - 100
EP - 100
VL - 26
IS - 1
DP - DeepDyve
ER -