TY - JOUR
AU - Jackson, Leila
AB - THE RENAL CHANGES IN RABBITS INOCULATED WITH STREPTOCOCCI* E. R. L E C 0 U N T AND LEI L A J AC K SON (From the Laboratory of St. Luke's Hospital, Chicago, Ill.) A number of writers have commented on the difficulties in pro­ ducing chronic nephritis in animals. Ophiils' says "a very serious obstacle to experiments of this kind is the spontaneous occurrence of chronic nephritis in the animals used. Even in rodents, chronic nephritis does occasionally occur spontaneously." And Pearce" says: "It must be admitted that the experimental study of nephritis supports the more common conception of the etiology of chronic' nephritis in man, that is, that it is a gradually developing lesion due to long con­ tinued insidious action of some ill defined toxic substance. With the pos­ sible exception of Dickson, the results obtained have been neither constant nor of such nature as to justify the term of chronic nephritis. Occasional positive findings, in view of the frequency of spontaneous lesions, must be regarded with suspicion." Dickson" also remarks that "a review of the literature on experimentally produced chronic nephritis forces one to the conclusion that the results obtained have not been very satisfactory." 
TI - The Renal Changes in Rabbits Inoculated with Streptococci
JF - The Journal of Infectious Diseases
DO - 10.1093/infdis/15.2.389
DA - 1914-09-01
UR - https://www.deepdyve.com/lp/oxford-university-press/the-renal-changes-in-rabbits-inoculated-with-streptococci-u0r00KQ0w5
SP - 389
EP - 408
VL - 15
IS - 2
DP - DeepDyve
ER -