TY - JOUR
AU - Romero, Romer A.
AB - A graphite furnace atomic absorption spectrometric (GFAAS) method for the determination of lead in whole blood specimens has been developed. Blood was diluted ten-fold with 0.01%/ Triton X-100 solution; 10 µl of diluted blood and 10 µl of a matrix modified mixture [0.6%/NHHPO and 0.15%/Mg(NO) in 0.01  HNO] were automatically injected in sequence into pyrolytic graphite coated graphite tubes. For comparison purposes, atomisation from a L'vov platform was also carried out. A 0.2-nm slit width was required in order to overcome spectral interference. The characteristic masses were 23 and 15 pg of Pb per 0.0044 A s for the pyrolytic graphite coated tube and L'vov platform, respectively. In the diluted solutions, the detection limits (3σ) for the method described were 1.2 µg l of Pb (pyrolytic graphite tube) and 0.7 µg l of Pb (L'vov platform). The accuracy of the method was tested using NBS SRM 955 (a mean relative error of  1% was obtained) and recovery studies were undertaken (average recoveries were 102%, range 95–105%). The precision was acceptable and an approximate standard deviation (SD) of 0.8 µg l of Pb was found for both within- and between-(day to day) run precision. The proposed method was used in studies of populations with a low risk of lead intoxication by environmental and/or occupational exposure; a mean (± SD) whole blood lead concentration of 110 ± 11 µg l(= 309 individuals) was found. The method was free from interference, reliable and reproducible.
TI - Determination of lead in whole blood by graphite furnace atomic absorption spectrometry with matrix modification
JO - Journal of Analytical Atomic Spectroscopy
DO - 10.1039/ja9890400401
DA - 1989-01-01
UR - https://www.deepdyve.com/lp/royal-society-of-chemistry/determination-of-lead-in-whole-blood-by-graphite-furnace-atomic-tkpVb2jhbC
SP - 401
EP - 406
VL - 4
IS - 5
DP - DeepDyve
ER -