TY - JOUR
AU - Dixon, K. W.
AB - A graft copolymer of L‐histidine on polyethylenimine has been demonstrated to be an efficient catalyst for the hydrolysis of activated phenyl esters in aqueous systems. A lack of any significant cooperative effects between neighboring imidazoles or amines has been shown by a study of the catalytic solvolysis of p‐nitrophenyl acetate at varying pH. A similar study with 4‐acetoxy‐3‐nitrobenzoic acid has displayed a bell‐shaped pH‐rate profile indicative of electrostatic interactions between the catalyst and substrate. Hydrophobic interactions were also evident from an investigation of the hydrolytic rates of a series of 4‐acyloxy‐3‐nitrobenzoic acids. In an attempt to demonstrate stereospecific catalyzed reactions, the hydrolyses of optically active esters catalyzed by the optically active copolymer were studied.
TI - Hydrolysis of activated esters catalyzed by L ‐histidine graft copolymers
JO - Journal of Polymer Science Polymer Chemistry Edition
DO - 10.1002/pol.1977.170150808
DA - 1977-08-01
UR - https://www.deepdyve.com/lp/wiley/hydrolysis-of-activated-esters-catalyzed-by-l-histidine-graft-tCMH9yNyX3
SP - 1863
EP - 1868
VL - 15
IS - 8
DP - DeepDyve
ER -