TY - JOUR
AU - Roets, D.E.
AB -  THE INFLUENCE OF SOME ANTHELMINTIC DRUGS ON THE POPULATION GROWTH OF THE FREE-LIVING NEMATODES CAENORHABDITIS BRIGGSAE AND TURBATRIX ACETI (NEMATODA : RHABDITIDA) BY J. R. VANFLETEREN and D. E. ROETS Instituut voor Dierkunde, Rijksuniversiteit Gent, Belgium Drugs with specific and intensive toxicity to nematodes, termed nematicides, might be suitable for the isolation of nematicide-resistant mutants. For this purpose, several medical anthelmintics, namely ascaridol, bephenium, d-tubocurarine chloride, piperazine adipate, piperazine hydrate, phenothiazine, n-hexylresorcinol, dithiazanine iodide, pyrvinium pamoate and thiabendazole have been tested for their influence on the population growth of Caenorhab- ditis briggsae and Turbatrix aceti. Ascaridol, bephenium, d-tubocurarine chloride, piperazine adipate, piperazine hydrate, phenothiazine and n-hexylresorcinol were shown to have a small to moderate toxicity. The effect of thiabendazole on population growth of C. briggsae is moderate, but its action on T. aceti is intense. Finally, dithiazanine iodide and pyrvinium pamoate are very toxic to both nematodes. It is concluded that dithiazanine iodide, pyrvinium pamoate and thiabendazole (restricted to T. aceti) might be suitable for the isolation of resistant mutants. Since the early work on the axenic cultivation of free-living nematodes, an in- creasing amount of information on the nutrition, physiology and biochemistry of these organisms has appeared. 
TI - The Influence of Some Anthelmintic Drugs On the Population Growth of the Free-Living Nematodes Caenorhabditis Briggsae and Turbatrix Aceti (Nematoda : Rhabditida)
JF - Nematologica
DO - 10.1163/187529272X00593
DA - 1972-01-01
UR - https://www.deepdyve.com/lp/brill/the-influence-of-some-anthelmintic-drugs-on-the-population-growth-of-t6qW5MQnwP
SP - 325
EP - 338
VL - 18
IS - 3
DP - DeepDyve
ER -