TY - JOUR
AU1 - Bartolozzi, Carlo
AU2 - Cioni, Dania
AU3 - Donati, Francescamaria
AU4 - Lencioni, Riccardo
AB -  Magnetic resonance signal intensity of focal liver lesions is affected by numerous pathologic factors. Lesion histologic features, such as cellularity, vascularity, stromal component, and intratumoral necrosis or hemorrhage, strongly affect T1 and T2 relaxation times. Additionally, intracellular content of certain substances, such as glycogen, fat, melanin, iron, and copper, may also have a substantial role in determining MR signal behavior. In this review we discuss the correlations between MR imaging features and pathologic findings in benign and malignant focal liver lesions. Knowledge of imaging–pathology correlations greatly assist in characterizing focal lesions. Moreover, in certain tumor histotypes, such as hepatocellular carcinoma, careful analysis of lesion signal intensity may help predict the degree of tumor differentiation.
TI - Focal liver lesions: MR imaging–pathologic correlation
JF - European Radiology
DO - 10.1007/s003300100845
DA - 2014-04-27
UR - https://www.deepdyve.com/lp/springer-journals/focal-liver-lesions-mr-imaging-pathologic-correlation-t2ColCph05
SP - 1374
EP - 1388
VL - 11
IS - 8
DP - DeepDyve
ER -