TY - JOUR
AU - He, Lanyan
AB - Re-fracture risk is higher following osteoporotic fracture. However, there is no accurately reported rate of re-fracture inci- dence in southwest China. The purpose of this study was to describe the osteoporotic vertebral fracture (OVF) survival for re-fracture state and analyze the risk of re-fracture. This historical cohort study was conducted in four hospitals in southwest China. Patients aged ≥ 50 years (n = 586) with OVF who were supposed to receive anti-osteoporosis drugs after the fracture were included (2012–2017). Telephone follow-up and referring case files were used to estimate the survival for re-fracture and identify the determinants of re-fracture. A total of 555 patients completed the follow-up investigation. Overall, 285 patients experienced a re-fracture, and the longest follow-up investigation time was 72 months. The survival rates for re-fracture at 12 months, 24 months, 36 months, and 48 months were 82.0%, 71.5%, 61.7%, and 34.0%, respectively. The factors correlated with re-fracture hazard were advanced age [hazard ratio (HR) = 1.996], being female (HR = 1.342), smoking (HR = 1.435), history of hypertension (HR = 1.219) and diabetes (HR = 3.271), and persistence of taking anti-osteoporosis drugs after fracture [0–3 months, 4–6 months, 7–12 months, and more than 12 months (HR = 0.703)]. OVF patients with advanced age, who were female, 
TI - Re-fracture and correlated risk factors in patients with osteoporotic vertebral fractures
JF - Journal of Bone and Mineral Metabolism
DO - 10.1007/s00774-018-0974-4
DA - 2018-11-21
UR - https://www.deepdyve.com/lp/springer-journals/re-fracture-and-correlated-risk-factors-in-patients-with-osteoporotic-sgQQX5D2gr
SP - 1
EP - 7
VL - OnlineFirst
IS - 
DP - DeepDyve
ER -