TY - JOUR
AU - Rosenow, Edward C.
AB - A PRECIPITATING AND NEUTRALIZING SCARLATINAL ANTI STREPTOCOCCUS HORSE SERUM EDW ARD C. ROSENOW From the Division of Experimental Bacteriology, The Mayo Foundation, Rochester, Minn. In the course of immunologic studies, and the injection into animals of freshly isolated strains of streptococci in the green-producing group, I have noted many examples of extreme specificity. Strains culturally and morphologically much alike often manifested widely different localiz­ ing and agglutinating properties. Moreover, marked changes in these properties occurred following cultivation on artificial mediums and many successive animal passages.' These changes were sometimes so striking as to suggest that a single strain may cause different diseases, depending on peculiar acquired infecting power and other properties, thus sup­ porting clinical and epidemiologic observations. During a mild outbreak of scarlet fever in Rochester in 1917, I noted at the time of infection in one family, a sequence of events which indicated that similar changes occur in the group of hemolytic streptococci. The two members of the family who first became ill developed hemolytic streptococcus infection of the throat, without rash; those next affected developed typical scarlet fever, while those affected last developed only the throat infection. Epidemics of scarlet fever rarely occur except when hemolytic 
TI - A Precipitating and Neutralizing Scarlatinal Antistreptococcus Horse Serum
JO - The Journal of Infectious Diseases
DO - 10.1093/infdis/36.6.525
DA - 1925-06-01
UR - https://www.deepdyve.com/lp/oxford-university-press/a-precipitating-and-neutralizing-scarlatinal-antistreptococcus-horse-scDN90YN7k
SP - 525
EP - 537
VL - 36
IS - 6
DP - DeepDyve
ER -