TY - JOUR
AU1 - Wang, Xiao-Chen
AU2 - Zhu, Dong-Min
AU3 - Shan, Yu-Xuan
AB - Am J Cardiovasc Drugs (2015) 15:429–437 DOI 10.1007/s40256-015-0134-3 SYSTEMATIC REVIEW Dobutamine Therapy is Associated with Worse Clinical Outcomes Compared with Nesiritide Therapy for Acute Decompensated Heart Failure: A Systematic Review and Meta-Analysis 1,2 3,4 5 • • Xiao-Chen Wang Dong-Min Zhu Yu-Xuan Shan Published online: 28 June 2015 Springer International Publishing Switzerland 2015 Abstract Methods Published studies related to dobutamine and Background Inotropes and natriuretic peptides are nesiritide therapy in ADHF were identified via an essential components of current therapeutic options for exhaustive search of scientific literature databases. The acute decompensated heart failure (ADHF). This system- identified studies, published between 2002 and 2012, were atic review examines the therapeutic effectiveness of carefully screened based on our predefined inclusion cri- dobutamine and brain natriuretic peptide, nesiritide, in teria. Selected studies were pooled, and odds ratios (ORs) reducing mortality and readmission rates for ADHF and 95 % confidence intervals (95 % CI) for each outcome treatment. were calculated. Subgroup analysis was conducted to assess the influence of ethnicity on the study outcome. Results Seven cohort studies were selected for this meta- analysis. These seven studies included 959 ADHF patients who underwent nesiritide treatment and 1748 ADHF patients who received dobutamine therapy. 
TI - Dobutamine Therapy is Associated with Worse Clinical Outcomes Compared with Nesiritide Therapy for Acute Decompensated Heart Failure: A Systematic Review and Meta-Analysis
JF - American Journal of Cardiovascular Drugs
DO - 10.1007/s40256-015-0134-3
DA - 2015-06-28
UR - https://www.deepdyve.com/lp/springer-journals/dobutamine-therapy-is-associated-with-worse-clinical-outcomes-compared-rz0Z3batVW
SP - 429
EP - 437
VL - 15
IS - 6
DP - DeepDyve
ER -