TY - JOUR AU - Langjoen, H. AB - 408 Abstracts of 16th Annual Meeting neuropsychological effects or cognitive decline. Additional research is warranted to assess the long-term implications of the procedure on the disease state. Soukup, V. M., Kertonen, L. M., Arunkumar, G. S., & Langjoen, H. Herpes simplex encephalitis (HSE) has been traditionally associated with a permanent, pervasive amnestic syndrome involving bilateral limbic system lesions. However, much of the literature regarding the cognitive effects in HSE predates the availability of acyclovir for treatment. Recent reports describe a high frequency of asymmetric pathology and distinct differences in the profiles of amnesia. This paper provides a summary of the clinical features, common neuroanatomical substrates of HSE, and prognostic factors reported since the introduction of acyclovir. A sample case, illustrating asymmetric involvement of the left temporal lobe is presented via serial MRI scans with 1.5T unit. An abbreviated neuropsy- chological protocol is described for use in bedside consultations. Follow-up evaluations performed at 6, 12, and 18 months corroborate the initial clinical impressions and provide preliminary support for the usefulness of these procedures in detecting areas of impairment and residual functions following anti-viral therapy. Spangenberg, K. B., Wagner, M. T., Bachman, D. L., & Hendrix, S. Delusional Misidentification Symptom (Mirror TI - Does acyclovir alter the cognitive sequelae in herpes simplex encephalitis? JF - Archives of Clinical Neuropsychology DO - 10.1093/arclin/12.4.408a DA - 1997-01-01 UR - https://www.deepdyve.com/lp/oxford-university-press/does-acyclovir-alter-the-cognitive-sequelae-in-herpes-simplex-rvILk07nAC SP - 408 EP - 408 VL - 12 IS - 4 DP - DeepDyve ER -