TY - JOUR AU1 - Zaanan, Aziz AU2 - Palle, Juliette AU3 - Soularue, Emilie AU4 - Leroy, Florence AU5 - Louafi, Samy AU6 - Tougeron, David AU7 - Manfredi, Sylvain AU8 - Artru, Pascal AU9 - Pozet, Astrid AU1 - Taieb, Julien AB - Targ Oncol (2018) 13:107–112 https://doi.org/10.1007/s11523-017-0531-4 SHORT COMMUNICATION Trastuzumab in Combination with FOLFIRI in Patients with Advanced HER2-Positive Gastro-Esophageal Adenocarcinoma: A Retrospective Multicenter AGEO Study 1,2 3 4 5 6 Aziz Zaanan & Juliette Palle & Emilie Soularue & Florence Leroy & Samy Louafi & 7 8 9 10 1,2 David Tougeron & Sylvain Manfredi & Pascal Artru & Astrid Pozet & Julien Taieb Published online: 31 October 2017 Springer International Publishing AG 2017 Abstract advanced gastro-esophageal adenocarcinoma treated with Background Trastuzumab with fluoropyrimidine and cisplatin is FOLFIRI plus trastuzumab between 2012 and 2015. the standard first-line treatment in patients with HER2-positive Results A total of 33 patients (median age, 60.3; performance advanced gastro-esophageal adenocarcinoma. However, there status 0–1, 78.8%) with HER2-positive advanced gastro- are no safety and efficacy data of trastuzumab with FOLFIRI. esophageal adenocarcinoma treated with FOLFIRI plus Objective To evaluate safety and efficacy of FOLFIRI plus trastuzumab in first (n = 3), second (n = 20) or third (n =10) trastuzumab in patients with HER2-positive advanced line of chemotherapy were included. There was one case of a gastro-esophageal adenocarcinoma. severe non-hematological adverse event corresponding to a left Patients and Methods This retrospective multicenter study ventricular systolic dysfunction. TI - Trastuzumab in Combination with FOLFIRI in Patients with Advanced HER2-Positive Gastro-Esophageal Adenocarcinoma: A Retrospective Multicenter AGEO Study JF - Targeted Oncology DO - 10.1007/s11523-017-0531-4 DA - 2017-10-31 UR - https://www.deepdyve.com/lp/springer-journals/trastuzumab-in-combination-with-folfiri-in-patients-with-advanced-her2-ruFWl2s1Vv SP - 107 EP - 112 VL - 13 IS - 1 DP - DeepDyve ER -