TY - JOUR AU - Bortz, Walter AB - Journal of Gerontology: Medical ScienceS © The author 2009. Published by Oxford University Press on behalf of The Gerontological Society of america. cite journal as: J Gerontol a Biol Sci Med Sci all rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org. 2010 Vol. 65A, No. 3, 255–256 advance access published on november 3, 2009 doi:10.1093/gerona/glp162 editorial Walter Bortz Stanford University School of Medicine, Bolivar Lane, Portola Valley, California. he report of Linda Fried and colleagues (1) in this is- moment. Our neocentric x fi ation always struggles with time. Tsue extends and complements their consecutive effort Richard Dawkins (6) points out how even e instein had to build a rigorous conceptual framework of frailty. The im- difficulty in reconciling time with his formulations. portance of the topic and its general lack of address endorse The insertion of a time dimension in our understanding of the significance of these data. frailty introduces the important process of phenotypic plas- For me, the most important new insight is provided by the ticity .The details of how the organism conforms its struc- authors’ strong suggestion that the nonlinearity of the mul- ture to a particular environmental field is now known in tiple system defects TI - Understanding Frailty JF - The Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences DO - 10.1093/gerona/glp162 DA - 2009-11-03 UR - https://www.deepdyve.com/lp/oxford-university-press/understanding-frailty-rS5oPQ2y7r SP - 255 EP - 256 VL - 65A IS - 3 DP - DeepDyve ER -