TY - JOUR
AU1 - Gupta, A.
AU2 - Shukla,  G. S.
AB - Bull. Environ, Contam. Toxicol. (1997) 58:198-205 © 1997 Springer-Verlag New York Inc. Enzymatic Antioxidants in Erythrocytes Following Heavy Metal Exposure: Possible Role in Early Diagnosis of Poisoning A. Gupta, G. S. Shukla Predictive Toxicology Research Group, Industrial Toxicology Research Centre, M. G. Marg, Post Box No. 80, Lucknow 226 001, India Received: 5 June 1996/Accepted: 12 September 1996 Occupational and environmental exposure to heavy metals such as cadmium, mercury, nickel, and lead is known to cause health hazards due to their toxic action on the biological system. Metals have the potential to cause oxidative damage to various tissues, including erythro– Since erythrocytes are likely to cytes (Sugiyama 1994) . be the primary target site for metal–induced damage, Eryth– they may be useful as an early diagnostic tool. rocytes are equipped with a variety of biochemical mechanisms operating against cellular damage. One such line of defense is provided by the enzymatic and non– enzymatic antioxidant system which helps to detoxify highly reactive species such as superoxide anion radi– cals, hydrogen peroxide, and hydroxyl radicals that are being generated during oxidative stress (Gelman et al. 1978). Therefore, in the present study cadmium (Cd), chromium (Cr), nickel (Ni), mercury (Hg), lead (Pb), 
TI - Enzymatic Antioxidants in Erythrocytes Following Heavy Metal Exposure: Possible Role in Early Diagnosis of Poisoning
JF - Bulletin of Environmental Contamination and Toxicology
DO - 10.1007/s001289900320
DA - 1997-02-01
UR - https://www.deepdyve.com/lp/springer-journals/enzymatic-antioxidants-in-erythrocytes-following-heavy-metal-exposure-rOMw9aQ99e
SP - 198
EP - 205
VL - 58
IS - 2 
DP - DeepDyve
ER -