TY - JOUR AU - Baseman, Joel B. AB - THE JOURNAL OF INFECTIOUS DISEASES. VOL. 136, NO.2. AUGUST 1977 © 1977 by the University of Chicago. All rig'hts reserved. NEvVS Summary of the Workshop on the Biology of interrupting and preventing the disease, and fu­ Treponema pallidum: Cultivation and ture research direction. Vaccine Development Metabolism Syphilis remains a serious disease of high inci­ dence, ranking among the most reported com­ Attempts to grow virulent T. pallidum in pure municable diseases in the United States and oth­ culture have failed, and earlier reports that indi­ er countries. The decline that has occurred in cated successful in vitro cultivation in cell· free total reported cases of syphilis during the past media cannot be reproduced. During the past five years is directly attributable to reductions in few years, research efforts have been directed to­ late and late latent syphilis. The frequency of pri­ ward defining metabolic capabilities and defi­ mary, secondary, and early latent syphilis has in­ ciencies of T. pallidum freshly extracted from creased during this same period. Considering the infected testes of rabbits in which virulent trepo­ number of unreported cases and the large reser­ nemes are routinely passaged. Such studies have voir of untreated and infectious individuals, there TI - From the National Institutes of Health JF - The Journal of Infectious Diseases DO - 10.1093/infdis/136.2.308 DA - 1977-08-01 UR - https://www.deepdyve.com/lp/oxford-university-press/from-the-national-institutes-of-health-rJ1XFrgDcm SP - 308 EP - 311 VL - 136 IS - 2 DP - DeepDyve ER -