TY - JOUR
AU1 - Punnoose, Mamatha Susan
AU2 - Mathew, Beena
AB - An eco-friendly and one-step microwave-assisted green synthesis of gold nanoparticles (AuNP) was developed using the aqueous leaf broth of Cyanthillium cinereum (CC) as the reducing and stabilizing agent. The progress of such bioconstituents stimulated experimental methods for the synthesis of gold particles in nanoregime is a key branch of nanotechnology due to its simple, sustainable and cost-effective nature. The prepared AuNP-CC particles were characterized using UV–vis., FT-IR, XRD, TEM, DLS and zeta potential analyses. The UV–vis. spectrum shows a surface plasmon resonance (SPR) at 548 nm. The FT-IR result proves the ability of CC extract to act as good capping and stabilizing agent for the nanoparticles. The high crystallinity of the AuNP-CC with face-centered cubic lattice phase was evident from XRD which is in accordance with bright circular rings of the obtained SAED patterns corresponding to (100), (200), (220) and (311) planes. The different morphologies and the estimated average nanoparticle size of 14.90 nm were analyzed using TEM. The negative zeta potential of − 19.2 mV suggested the stability of the formed nanoparticles. DLS measurement confirmed the diameter of nanoparticles to be in nanoscale. The catalytic potential of the AuNP-CC toward degradation of o-/p-nitro anilines was evaluated. The rapid catalytic reductions were monitored and found that they followed pseudo-first-order kinetic model. The linear dependence of the reaction rate constants with increase in catalytic dosage was also assessed. The cytotoxic activity of CC leaf extract and the gold nanoparticles were studied on human lung cancer cell line A549 using MTT assay. Studies shown that the cell viability (%) decreases with increasing sample dose, and nanoparticles have more toxic effect on the cancer cell than the pure CC extract. LC50 values were determined to be 110.19 ± 0.19 μg/mL and 87.92 ± 0.30 μg/mL for CC extract and AuNP-CC, respectively. The antibacterial activity of AuNP-CC was evaluated against four different human pathogenic bacteria. The excellent catalytic efficiency, cytotoxic and antibacterial activities of the green synthesized AuNP-CC are of great environmental benefits.
TI - Microwave-assisted green synthesis of Cyanthillium cinereum mediated gold nanoparticles: Evaluation of its antibacterial, anticancer and catalytic degradation efficacy
JF - Research on Chemical Intermediates
DO - 10.1007/s11164-021-04641-1
DA - 2022-03-01
UR - https://www.deepdyve.com/lp/springer-journals/microwave-assisted-green-synthesis-of-cyanthillium-cinereum-mediated-qrXlba20wc
SP - 1025
EP - 1044
VL - 48
IS - 3
DP - DeepDyve
ER -