TY - JOUR AU - Luban, Naomi L.C. AB - NAOMI L.C. LUBAN Keywords: Pediatric transfusion, CMV, Graft -vs- Host Introduction Advances in the care of the critically ill newborn have necessitated dramatic changes in the blood bank’s response to the needs of these infants, especially premature infants. The neonate must now be considered a major consumer of blood products, and the packaging and administration of these products must be altered to suit their specialized needs. This lecture will address many aspects of transfusion therapy by blood product type and will review safety, efficacy, packaging, and administration. Rationale for transfusion Low birth weight infants will require transfusions for one of several reasons. Many of the transfusions are needed because of iatrogenic blood loss for laboratory tests and blood gas analysis. The sicker the infant, the more blood sampling and the greater the exposure to red blood cell, platelet and plasma products [1,2]. Other RBC transfusions are administered for clinical indications such as respiratory distress syndrome, poor weight gain, tachycardia, apnea, tachypnea, or to simply maintain a predetermined hemoglobin concentration. Based on a review of data in the literature and that collected by the American Association of Blood Bank’s Pediatric Hemotherapy Committee, a mean of 8 to 10 different donor TI - Management of pediatric transfusions JF - Vox Sanguinis DO - 10.1159/000462740 DA - 2017-01-01 UR - https://www.deepdyve.com/lp/karger/management-of-pediatric-transfusions-qmUpM2vz1j SP - 229 EP - 234 VL - 67 IS - Suppl 3 DP - DeepDyve ER -