TY - JOUR AU - Inaba, Kenji AB - PRESENTED PAPER Kenji Inaba, MD, FACS n the acute resuscitation of critically ill trauma patients who For developing countries without a stable regional Ihave sustained blood loss, there has been a shift toward the supply or in the military setting, however, the traditional 1–5 aggressive use of blood component therapy. Driven by an system for plasma storage and dispensing is less than 6–8 increasing evidence base derived from both the military optimal; and a dried product would be beneficial from 9 –17 and civilian experience, aggressive plasma infusion in several vantage points. The primary advantage would be particular has become widely practiced. For patients who storage and transportation. A product that is shelf stable, require a massive transfusion, defined in the majority of pub- tolerant to ambient temperature, and easily portable would lished research protocols as 10 units of packed red blood cells allow greater flexibility in where plasma could be given. within the first 6 hours to 24 hours, plasma infusion in ratios Preparation would also be streamlined when compared approaching 1:1 has been associated in multiple retrospective with the thawing process required for frozen plasma. The studies with an improvement in survival. solution, in theory, could also TI - Freeze-Dried Plasma JF - The Journal of Trauma: Injury, Infection, and Critical Care DA - 2011-05-01 UR - https://www.deepdyve.com/lp/wolters-kluwer-health/freeze-dried-plasma-qlICVCvfhy SP - - VL - 70 IS - DP - DeepDyve ER -