TY - JOUR
AU - Forest Huddleson, I.
AB - ANTICOMPLEMENTARY ACTION FRESH OF BOVINE SERUM I. FOREST HUDDLESON From tile Laboratory of Bacteriology and H)'giene, MichigaJl Agricultural Esperim~Jlt Station, East Lansing Complement fixation in conjunction with agglutination has been employed successfully in the diagnosis of bovine infectious abortion for a number of years. During the past" few years, however, many investigators have abandoned the fixation test in favor of agglutination, for different reasons. One says there is too much work involved; another that the two tests agree so closely it is unnecessary to use both; another that the fixation test is unreliable because of the appear­ ance of unexplained factors which interfere with accurate interpreta­ tions.' The latter difficulty is the subject of this paper. There seems to have been a wrong assumption in regard to the properties of bovine serum from the beginning of the use of the fixation test in the diagnosis of bovine infectious abortion, based on the belief that serum from all species of animals contains native comple­ ment in sufficient quantity to disturb the accuracy of the test, in case complement from another source is added also. This belief has led workers to heat all serum at 56 C. for 30 minutes to 
TI - Anticomplementary action of fresh bovine serum
JF - The Journal of Infectious Diseases
DO - 10.1093/infdis/33.2.184
DA - 1923-08-01
UR - https://www.deepdyve.com/lp/oxford-university-press/anticomplementary-action-of-fresh-bovine-serum-qfIzD9H6Y4
SP - 184
EP - 192
VL - 33
IS - 2
DP - DeepDyve
ER -