TY - JOUR
AU - Sollberger, Gabriel
AB - Cell death is an integral part of both infectious and sterile inflammatory reactions. Many cell death pathways cause the dying cell to lyse, thereby amplifying inflammation. A special form of lytic cell death is the formation of neutrophil extracellular traps (NETs), large structures of chromatin and antimicrobial proteins, which are released by dying neutrophils to capture extracellular pathogens and limit the spread of infections. The molecular mechanisms of NET formation remain incompletely understood. Recent research demonstrated substantial crosstalk between different cell death pathways, most notably between apoptosis, pyroptosis and necroptosis. Here, we review suicidal and vital NET formation and discuss potential crosstalk of their mechanisms of release with other forms of cell death.
TI - NET formation – mechanisms and how they relate to other cell death pathways
JO - The Febs Journal
DO - 10.1111/febs.15589
DA - 2021-06-01
UR - https://www.deepdyve.com/lp/wiley/net-formation-mechanisms-and-how-they-relate-to-other-cell-death-qZ8mjAzli0
SP - 3334
EP - 3350
VL - 288
IS - 11
DP - DeepDyve
ER -