TY - JOUR
AU - Marchbank, Adrian
AB - 67- Adrian Marchbank National Heart and Institute, London Lung tion allowed survival.5,6 Introduction and Stability consistency of emulsification with various Perfluorocarbon as Interest in fluorocarbons was achieved Clark who used synthetic oxygen compounds by carriers was initiated the Pluronic as a surfactant and used the emulsion by astonishing reports in 1966 that mice immersed in fluorocarbon in and with few side- successfully dogs monkeys could breathe for several hours’ and effects liquid survived when were returned to The with the emulsions they breathing major problem early in the scientific was the short and tissue half-lives gas. Accompanying photographs plasma long caused considerable interest. Use as a of the different fluorocarbons and press available, ’blood substitute’ was on the the limited of fluorocarbon in suggested grounds availability large that the function of an isolated rat heart could but of sufficient for animal quantities, purity be when with standardization of supported alternately perfused experimentation. Gradually, blood and fluorocarbon resulted in commercial (FX80, predominantly techniques preparations it was available in in 1978 However, perfluorobutyltetrahydrofuran) .2 becoming Japan (Fluosol 43).9 unsuitable for use as a Initial clinical trials in of use in anaemia intravenously consequence Japan of its with blood. In order or 
TI - Fluorocarbon emulsions: 
JF - Perfusion
DO - 10.1177/026765919501000203
DA - 2016-06-30
UR - https://www.deepdyve.com/lp/sage/fluorocarbon-emulsions-qWmwg9QFkl
SP - 67
EP - 88
VL - 10
IS - 2
DP - DeepDyve
ER -