TY - JOUR
AU - FERGUSON-SMITH, M A
AB - British Medical Bulletin (1983) Vol. 39, No . 4, pp. 365-372 MATERNAL SERUM a-FP SCREENING FOR NEURAL TUBE DEFECTS M A Ferguson-Smith availability of obstetric resources, and about the possible loss of normal pregnancies from the complications of amniocentesis or from false-positive amniotic alphafetoprotein (ama-FP) results. The likely rate of compliance among pregnant women, the THE REDUCTION OF ANENCEPHALIC availability of ultrasound for checking the period of gestation, and AND SPINA BIFIDA BIRTHS the ability of MSa-FP to identify other fetal abnormalities and multiple pregnancy were largely unknown. From 1971-1975, the BY MATERNAL SERUM birth incidence of neural tube defects varied from 5.2 per 1000 in ALPHAFETOPROTEIN SCREENING Wales to 3.3 per 1000 in East Anglia (see Office of Population Censuses and Surveys, 1983), and it was uncertain whether or not screening should be confined to high-risk areas or be made M A FERGUSON-SMITH FRCPath FRCP FRS available to all mothers. A number of prospective studies have now been published Duncan Guthrie Institute of Medical Genetics (Table I) and it seems an appropriate time to review the efficacy of University of Glasgow MSa-FP screening as revealed by this experience. Many of the practical aspects to be considered here are 
TI - THE REDUCTION OF ANENCEPHALIC AND SPINA BIFIDA BIRTHS BY MATERNAL SERUM ALPHAFETOPROTEIN SCREENING
JF - British Medical Bulletin
DO - 10.1093/oxfordjournals.bmb.a071849
DA - 1983-01-01
UR - https://www.deepdyve.com/lp/oxford-university-press/the-reduction-of-anencephalic-and-spina-bifida-births-by-maternal-qOWozbWD00
SP - 365
EP - 372
VL - 39
IS - 4
DP - DeepDyve
ER -