TY - JOUR AU - Salter, D.C. AB - l88 T.J.Ryan Addendum. The effect of coldness upon connective tissue mechanics in the aetio- logy of Raynaud's phenomenon and 'vibration white finger' The mechanical effect of coldness is to change the compliance of the connective tissue environ- ment in which the microvasculature should carry out its pulsatile perfusion. As the tempera- ture of the connective tissue decreases, so does its compliance, and the tiny vessels are less and less able to pulse open enough to provide an adequate flux of blood, or to help pump interstitial fluid into and along the lymphatics. Even a simplistic analysis of this situation, however, demands such formidable mathematics (Dean, t939) that the topic has been conveniently forgotten, and this is unfortunate because a mere order-of-magnitude calculation shows it to be far too big an effect to be ignored. Such a calculation will be presented here. When considering the passage of a pulse of blood through a microvessel immersed in the dermis we are concerned mainly with the complex shear compliance, J*((w), where w is the angular frequency of movement of the connective tissue, and will be low. This compliance is the reciprocal of G*(to), the complex shear modulus, dealt with by theories of TI - Addendum. The effect of coldness upon connective tissue mechanics in the aetiology of Raynaud's phenomenon and ‘vibration white finger’ JF - Clinical and Experimental Dermatology DO - 10.1111/j.1365-2230.1981.tb02288.x DA - 1981-03-01 UR - https://www.deepdyve.com/lp/oxford-university-press/addendum-the-effect-of-coldness-upon-connective-tissue-mechanics-in-q6aBOJ8Khv SP - 188 EP - 189 VL - 6 IS - 2 DP - DeepDyve ER -