TY - JOUR AU1 - Kagan, Irving G. AB - EXPERIMENTAL INFECTIONS OF RHESUS MONKEYS WITH SCHISTOSOMATIUM DOUTHITTI (CORT, 1914) IRVING G. KAGAN From the Zoological Laboratory, University of Pennsylvania, Philadelphia 4, Pennsylvania In the United States bathers are oc­ systemic infections with animal schisto­ casionally exposed to the cercariae of somes. several bird and at least one mammalian In a series of experiments reported in schistosome. Penetration into the skin this paper this hypothesis was critically by these cercariae may, in a sensitized tested. The development of S. douthitti individual, produce a schistosome der­ was studied in rhesus monkeys, Macaca matitis. The fate of these cercariae in mulatta, exposed to large numbers of man is unknown although it is currently cercariae and autopsied at closely believed from biopsies of skin tissue spaced intervals over a period of several that cercariae do not penetrate beyond weeks. Resistance experiments with the epidermal layers of the skin in monkeys exposed to S. douthitti against humans (Brackett, 1940a). Oliver the homologous species and against (1949a) exposed laboratory animals, in­ Schistosoma mansoni were also con­ cluding a rhesus monkey, to several ducted. species of bird schistosomes and ob­ MATERIALS AND METHODS served schistosome lesions in the lungs Four young rhesus monkeys (#1, 6, TI - Experimental Infections of Rhesus Monkeys with Schistosomatium Douthitti (Cort, 1914) JF - The Journal of Infectious Diseases DO - 10.1093/infdis/93.2.200 DA - 1953-07-01 UR - https://www.deepdyve.com/lp/oxford-university-press/experimental-infections-of-rhesus-monkeys-with-schistosomatium-pool29RCWV SP - 200 EP - 206 VL - 93 IS - 2 DP - DeepDyve ER -