TY - JOUR
AU1 - Kim, Harold H.
AU2 - Samadpour, Mansour
AU3 - Grimm, Linda
AU4 - Clausen, Carla R.
AU5 - Besser, Thomas E.
AU6 - Baylor, Michael
AU7 - Kobayashi, John M.
AU8 - Neill, Marguerite A.
AU9 - Schoenknecht, Fritz D.
AU1 - Tarr, Phillip I.
AB - The resistance of Escherichia coli O157:H7 to amoxicillin/clavulanic acid, ampicillin, ceftazidime, ceftriaxone, cefuroxime, cephalothin, chloramphenicol, ciprofloxacin, gentamicin, streptomycin, sulfisoxazole, tetracycline, ticarcillin, tobramycin, and trimethoprim-sulfamethoxazole was examined, and resistant strains were characterized. All 56 isolates collected between 1984 and 1987 were susceptible to all antibiotics tested; 13 (7.4%) of 176 strains isolated between 1989 and 1991 were resistant to streptomycin, sulfisoxazole, and tetracycline. A-restriction fragment length polymorphism analysis suggested that the 13 resistant strains belonged to nine different clones. The emerging resistance of E. coli O157:H7 to antibiotics could portend an increased prevalence of this pathogen in food animals that receive antibiotics. Antimicrobial resistance of E. coli O157:H7 could be useful as a rapid epidemiologic marker and as a way to select this pathogen from suspected vehicles of transmission, but this resistance could also complicate therapeutic trials with sulfa-containing antibiotics.
TI - Characteristics Of Antibiotic-Resistant Escherichia Coli O157:H7 In Washington State, 1984–1991
JF - The Journal of Infectious Diseases
DO - 10.1093/infdis/170.6.1606
DA - 1994-12-01
UR - https://www.deepdyve.com/lp/oxford-university-press/characteristics-of-antibiotic-resistant-escherichia-coli-o157-h7-in-pfPa0xoV2g
SP - 1606
EP - 1609
VL - 170
IS - 6
DP - DeepDyve
ER -