TY - JOUR AU1 - Van Cleemput, Tim AU2 - Jackers, Xander AU3 - Piagkou, Maria AU4 - Politis, Constantinus AB - PurposeOdontogenic keratocysts (OKCs) have high recurrence rates. We aimed to identify recurrence patterns in OKCs and the onset of second primary OKCs in non-syndromic and syndromic patients.Material and MethodsPatients with OKCs reporting to our department from 1998 to 2021 (23 years) were retrospectively evaluated using demographic, clinical (age, sex, location, and size), histopathological, radiographic, and treatment data. All patients were followed-up for > 3 years and evaluated for OKC recurrence. Patients with naevoid basal cell carcinoma syndrome (NBCCS) were evaluated separately.ResultsWe included 38 and 13 patients in the non-syndromic and syndromic OKC groups, respectively. The recurrence rates were 15.8 and 21.4% in the non-syndromic and syndromic groups, respectively; 8.9% of patients exhibited a second recurrence and 1.8% a third recurrence. No second primary OKCs were observed in the non-syndromic group; 76.9% of patients in the syndromic group developed at least one.ConclusionWe found a higher recurrence rate in patients with NBCCS compared with patients with non-syndromic OKCs (21.4 versus 15.8%). The probability of developing a second primary OKC in patients with NBCCS was higher compared with that in patients with non-syndromic OKCs (76.9 versus 0%). No statistically significant risk factors for OKC recurrence were identified. TI - Recurrence Patterns of Odontogenic Keratocysts in Syndromic and Non-Syndromic Patients JF - Journal of Maxillofacial and Oral Surgery DO - 10.1007/s12663-023-01920-9 DA - 2024-02-01 UR - https://www.deepdyve.com/lp/springer-journals/recurrence-patterns-of-odontogenic-keratocysts-in-syndromic-and-non-pKmDE4zZMP SP - 152 EP - 158 VL - 23 IS - 1 DP - DeepDyve ER -