TY - JOUR
AU - Einhorn, Stefan
AB - Human interferon (IFN) was examined for its capacity to modify the phytohaemagglutinin (PHA)-triggered release of mitogenic factors (MF) from human lymphocytes in vitro. It was observed that the presence of partially purified leukocyte IFN (IFN-α) during the PHA pulsing of the lymphocytes increased their subsequent release of factors which were mitogenic for fractionated T cells. A similar effect was also observed when lymphocytes were exposed to IFN-α prior to PHA pulsing. The possibility that substances in the IFN preparations other than IFN are responsible for the above effect is ruled out by the finding that a pure fibroblast IFN (IFN-β) preparation also augmented the MF release by PHA-pulsed lymphocytes.
TI - Lymphokine Production by PHA-Stimulated Human Lymphocytes is Enhanced by Interferon
JO - International Archives of Allergy and Immunology
DO - 10.1159/000232816
DA - 1981-01-01
UR - https://www.deepdyve.com/lp/karger/lymphokine-production-by-pha-stimulated-human-lymphocytes-is-enhanced-pEQO1q7xrb
SP - 173
EP - 178
VL - 66
IS - 2
DP - DeepDyve
ER -